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Category: Critical Care Medicine-Hematologic and Oncologic Disorders--->White Blood Cell Disorders
Page: 2

Question 6# Print Question

A 62-year-old male with a history of acute myeloid leukemia and allogeneic hematopoietic stem cell transplantation (HSCT) 2 months ago presents with cough, dyspnea on exertion, and fevers for 1 week. On examination, his temperature was 100.9°F, heart rate 100 beats/min, respiratory rate 20 breaths/min, and blood pressure 120/80 mm Hg. He appeared chronically ill with bibasilar crackles on auscultation. His white blood cell count was 3400 cells/µL and his chest radiograph showed bilateral lower lobe infiltrates.

Differential diagnosis includes all of the following EXCEPT:

A. Periengraftment respiratory distress syndrome
B. Bacterial pneumonia
C. Radiation pneumonitis
D. Idiopathic pneumonia syndrome


Question 7# Print Question

A 67-year-old male who presented with severe back pain and bilateral lower extremity weakness is admitted to the intensive care unit after emergent surgical spinal decompression and fixation. Bone marrow biopsy shows >10% clonal plasma cells.

Other criteria for the diagnosis of multiple myeloma include all the following EXCEPT:

A. MRI showing two or more focal bone or bone marrow lesions at ≥5 mm in size
B. Hypercalcemia
C. Recurrent infections
D. Creatinine clearance <40 mL/min


Question 8# Print Question

A 73-year-old male with a history of multiple myeloma presents with symptoms of nausea, abdominal pain, and lethargy. His serum calcium is 15 mg/dL.

Which of the following statements about the management of hypercalcemia is FALSE?

A. Risedronate is not recommended for the treatment of severe hypercalcemia
B. Calcitonin decreases bone resorption but takes 48 hours to see a decrease in serum calcium levels
C. Denosumab limits bone resorption by inhibiting receptor activator of nuclear factor kappa-B (RANKL)
D. Dialysis may be needed if he has renal failure due to hypercalcemia or multiple myeloma or both




Category: Critical Care Medicine-Hematologic and Oncologic Disorders--->White Blood Cell Disorders
Page: 2 of 2